Skin trouble test
Wheat germ extract
Skin sensitivity test data
To evaluate the antimicrobial activity of wheat germ
extract and its indicator component
(2,6-dimethoxy-1,4-benzoquinone, DMBQ) against
Propionibacterium acnes under anaerobic conditions,
and to confirm the reduction rate (%) of Propionibacterium
acnes.
EUW-2 was confirmed to have the minimum inhibitory
concentration (MIC) at a concentration of 78μg/mL,
while DMBQ extracted as the indicator component was
confirmed to have MIC at a concentration of 8μg/mL,
indicating its improved antimicrobial activity against acne.

To evaluate the antimicrobial activity of wheat germ
extract and assess its ability to inhibit the growth of five
test strains.
The killing time curves of the target strains were measured,
and the results showed that at concentrations above
5mg/mL, all Staphylococcus aureus were killed within 12
hours. The MIC was confirmed for EUQ-2 at a concentration
of 78μg/mL, while DMBQ extracted as the indicator
component confirmed MIC at a concentration of 8μg/mL,
indicating improved antimicrobial activity against acne.

To conduct clinical trials on wheat germ extract and
analyze the efficacy and side effects of the product.
The experimental group used a common product devoid
of active ingredients twice daily for 8 weeks.
Photographs were taken with a digital camera at the first
and last visits.
To confirm the frequency and severity of side effects,
symptoms reported by the subjects were recorded at each
visit.
Adding to the oil-free cream formulation
#1: Wheat germ extract 1%
#2: Wheat germ extract 2%,
pumpkin extract 0.2%,
green tea extract 0.2%,
pine needle extract 0.1%
After 4 weeks of product usage, compared to before
product usage, both the experimental group and the
control group showed a significant reduction in open
comedones, closed comedones, and papules (p<0.05),
but the experimental group showed a greater reduction in
magnitude.

In addition to managing the balance of water and oil,
excessive secretion of sebum can also lead to acne.
The purpose of this study is to confirm the sebum status
on the surface of the skin using a sebum analyzer.
Observations from the images reveal that the pores
appear relatively darker compared to the surrounding
areas and are circular in shape.

Compared to before using the test product (wheat germ
face cream), after 4 weeks of product usage, there was a
significant reduction in facial sebum levels. Moreover, this
reduction was significantly greater (improved) in the
experimental group compared to the control group
(p<0.05).

If the skin's oil content is high, the surface may feel greasy due to the oil, while the inside may suffer from lack of
moisture.
In order to regulate the balance of oil on the skin's surface and internally.
before and after 4 weeks of product usage, the skin's oil
quantity on both sides of the forehead was measured
once using the Sebumeter Sm810, and then analyzed.
A mat tape was placed on the cassette to absorb the oil
on the skin's surface, and then the cassette was placed
into the main slot for quantitative evaluation based on the
amount of light transmitted through the tape.
Compared to before product usage, after 4 weeks of
product usage, there was a significant reduction in facial
sebum levels in the cheek area. The experimental group
showed a significantly greater reduction (improvement)
compared to the control group.

control cream for acne-prone skin have been completed

To evaluate the safety and human efficacy of products
containing wheat germ extract, specifically the Spa Care
mineral mask.
The 24-hour long-lasting moisturizing effect and human
efficacy evaluation of the Spa Care mineral mask, as well as safety assessment, have been completed.
